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In Vitro Sensitization of T Cells with DC-Associated/Delivered HIV Constructs Can Induce a Polyfunctional CTL Response, Memory T-Cell Response, and Virus Suppression
The absence of a suitable animal model for HIV infection is one of the major obstacles to the development of a preventive HIV vaccine. Vaccines showing good response in animal studies may fail in human efficacy trials. We have demonstrated DC-mediated in vitro sensitization of autologous T cells aga...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Mary Ann Liebert, Inc.
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3271377/ https://ncbi.nlm.nih.gov/pubmed/22233251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/vim.2011.0055 |
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