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Diethylnitrosamine-induced hepatocarcinogenesis is suppressed in lecithin:retinol acyltransferase-deficient mice primarily through retinoid actions immediately after carcinogen administration

Loss of retinoid-containing lipid droplets upon hepatic stellate cell (HSC) activation is one of the first events in the development of liver disease leading to hepatocellular carcinoma. Although retinoid stores are progressively lost from HSCs during the development of hepatic disease, how this aff...

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Detalhes bibliográficos
Main Authors: Shirakami, Yohei, Gottesman, Max E., Blaner, William S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271263/
https://ncbi.nlm.nih.gov/pubmed/22116467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgr275
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