Vertebrate ultraviolet visual pigments: Protonation of the retinylidene Schiff base and a counterion switch during photoactivation

For visual pigments, a covalent bond between the ligand (11-cis-retinal) and receptor (opsin) is crucial to spectral tuning and photoactivation. All photoreceptors have retinal bound via a Schiff base (SB) linkage, but only UV-sensitive cone pigments have this moiety unprotonated in the dark. We inv...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Kusnetzow, Ana Karin, Dukkipati, Abhiram, Babu, Kunnel R., Ramos, Lavoisier, Knox, Barry E., Birge, Robert R.
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2004
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC327121/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14732701/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0305206101
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