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PET/CT Imaging of c-Myc Transgenic Mice Identifies the Genotoxic N-Nitroso-Diethylamine as Carcinogen in a Short-Term Cancer Bioassay

BACKGROUND: More than 100,000 chemicals are in use but have not been tested for their safety. To overcome limitations in the cancer bioassay several alternative testing strategies are explored. The inability to monitor non-invasively onset and progression of disease limits, however, the value of cur...

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Bibliografiske detaljer
Main Authors: Hueper, Katja, Elalfy, Mahmoud, Laenger, Florian, Halter, Roman, Rodt, Thomas, Galanski, Michael, Borlak, Juergen
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3271108/
https://ncbi.nlm.nih.gov/pubmed/22319569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030432
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