Self-associating block copolymer networks for microchip electrophoresis provide enhanced DNA separation via “inchworm” chain dynamics

We describe a novel class of DNA separation media for microchip electrophoresis, “physically crosslinked” block copolymer networks, which provide rapid (< 4.5 min) and remarkably enhanced resolution of DNA in a size range critical for genotyping. Linear poly(acrylamide-co-dihexylacrylamide) (LPA-...

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Hauptverfasser: Chiesl, Thomas N., Putz, Karl W., Babu, Meena, Mathias, Patrick, Shaikh, Kashan A., Goluch, Edgar D., Liu, Chang, Barron, Annelise E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270944/
https://ncbi.nlm.nih.gov/pubmed/16808448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac060193u
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