The Safety of EXPAREL ® (Bupivacaine Liposome Injectable Suspension) Administered by Peripheral Nerve Block in Rabbits and Dogs

A sustained-release DepoFoam injection formulation of bupivacaine (EXPAREL, 15 mg/mL) is currently being investigated for postsurgical analgesia via peripheral nerve block (PNB). Single-dose toxicology studies of EXPAREL (9, 18, and 30 mg/kg), bupivacaine solution (Bsol, 9 mg/kg), and saline injecte...

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Autori principali: Richard, Brigitte M., Newton, Paul, Ott, Laura R., Haan, Dean, Brubaker, Abram N., Cole, Phaedra I., Ross, Paul E., Rebelatto, Marlon C., Nelson, Keith G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270427/
https://ncbi.nlm.nih.gov/pubmed/22363842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/962101
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