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Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells
Taxanes remain first line chemotherapy in management of metastatic breast cancer and have a key role in epithelial ovarian cancer, with increasingly common use of weekly paclitaxel dosing regimens. However, their clinical utility is limited by the development of chemoresistance. To address this, we...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3270273/ https://ncbi.nlm.nih.gov/pubmed/22278287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.139 |
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