BRAF and PIK3CA genes are somatically mutated in hepatocellular carcinoma among patients from South Italy

Poor data have been previously reported about the mutation rates in K-RAS, BRAF, and PIK3CA genes among patients with hepatocellular carcinoma (HCC). Here we further elucidated the role of these genes in pathogenesis of primary hepatic malignancies. Archival tumour tissue from 65 HCC patients origin...

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Detalhes bibliográficos
Main Authors: Colombino, M, Sperlongano, P, Izzo, F, Tatangelo, F, Botti, G, Lombardi, A, Accardo, M, Tarantino, L, Sordelli, I, Agresti, M, Abbruzzese, A, Caraglia, M, Palmieri, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270270/
https://ncbi.nlm.nih.gov/pubmed/22258409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.136
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