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Impaired Gremlin 1 (GREM1) expression in cumulus cells in young women with diminished ovarian reserve (DOR)

PURPOSE: A symbiotic relationship between ovarian granulosa cells (GC) and the developing oocyte is critical. Genetic modulations in GC’s can lead to reproductive insufficiency, highlighting the role of GC’s in reproductive competence. Utilizing gene expression analyses in cumulus GC’s, we attempt t...

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Detalhes bibliográficos
Main Authors: Jindal, Sangita, Greenseid, Keri, Berger, Dara, Santoro, Nanette, Pal, Lubna
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270130/
https://ncbi.nlm.nih.gov/pubmed/22160428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10815-011-9684-8
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