Brainstem Deficiency of the 14-3-3 Regulator of Serotonin Synthesis: A Proteomics Analysis in the Sudden Infant Death Syndrome

Impaired brainstem responses to homeostatic challenges during sleep may result in the sudden infant death syndrome (SIDS). Previously we reported a deficiency of serotonin (5-HT) and its key biosynthetic enzyme, tryptophan hydroxylase (TPH2), in SIDS infants in the medullary 5-HT system that modulat...

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Détails bibliographiques
Auteurs principaux: Broadbelt, Kevin G., Rivera, Keith D., Paterson, David S., Duncan, Jhodie R., Trachtenberg, Felicia L., Paulo, Joao A., Stapels, Martha D., Borenstein, Natalia S., Belliveau, Richard A., Haas, Elisabeth A., Stanley, Christina, Krous, Henry F., Steen, Hanno, Kinney, Hannah C.
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2012
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270099/
https://ncbi.nlm.nih.gov/pubmed/21976671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.009530
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