Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Impairs the Regulation of Apoptosis in Megakaryocytes by Activating NF-κB: a Proteomic Study

We previously showed that the Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) and its receptor VPAC1 are negative regulators of megakaryopoiesis and platelet function, but their downstream signaling pathway that inhibits this process still remained unknown. A combined proteomic, transcrip...

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Detalhes bibliográficos
Main Authors: Di Michele, Michela, Peeters, Karen, Loyen, Serena, Thys, Chantel, Waelkens, Etienne, Overbergh, Lutgart, Hoylaerts, Marc, Van Geet, Christel, Freson, Kathleen
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270095/
https://ncbi.nlm.nih.gov/pubmed/21972247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.007625
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