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Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

Most human pre-mRNAs are spliced into linear molecules that retain the exon order defined by the genomic sequence. By deep sequencing of RNA from a variety of normal and malignant human cells, we found RNA transcripts from many human genes in which the exons were arranged in a non-canonical order. S...

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Bibliografiske detaljer
Main Authors: Salzman, Julia, Gawad, Charles, Wang, Peter Lincoln, Lacayo, Norman, Brown, Patrick O.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270023/
https://ncbi.nlm.nih.gov/pubmed/22319583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030733
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