Regrowing the Adult Brain: NF-κB Controls Functional Circuit Formation and Tissue Homeostasis in the Dentate Gyrus

Cognitive decline during aging is correlated with a continuous loss of cells within the brain and especially within the hippocampus, which could be regenerated by adult neurogenesis. Here we show that genetic ablation of NF-κB resulted in severe defects in the neurogenic region (dentate gyrus) of th...

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Détails bibliographiques
Auteurs principaux: Imielski, Yvonne, Schwamborn, Jens C., Lüningschrör, Patrick, Heimann, Peter, Holzberg, Magdalena, Werner, Hendrikje, Leske, Oliver, Püschel, Andreas W., Memet, Sylvie, Heumann, Rolf, Israel, Alain, Kaltschmidt, Christian, Kaltschmidt, Barbara
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270021/
https://ncbi.nlm.nih.gov/pubmed/22312433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030838
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