Association of COMT genotypes with S-COMT promoter methylation in growth-discordant monozygotic twins and healthy adults

BACKGROUND: Catechol-O-Methyltransferase (COMT) plays a key role in dopamine and estrogen metabolism. Recently, COMT haplotypes rather than the single polymorphism Val158Met have been reported to underlie differences in protein expression by modulating mRNA secondary structure. So far, studies inves...

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Detalhes bibliográficos
Main Authors: Schreiner, Felix, El-Maarri, Osman, Gohlke, Bettina, Stutte, Sonja, Nuesgen, Nicole, Mattheisen, Manuel, Fimmers, Rolf, Bartmann, Peter, Oldenburg, Johannes, Woelfle, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3270002/
https://ncbi.nlm.nih.gov/pubmed/21884617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-12-115
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