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Nitric Oxide Generation Affects Pro- and Anti-Angiogenic Growth Factor Expression in Primary Human Trophoblast
OBJECTIVES: Preeclampsia is associated with reduced trophoblast placenta growth factor (PGF) expression, elevated soluble fms-like tyrosine kinase-1 (sFlt-1) and decreased bioactivity of nitric oxide (NO). Elevated sFlt-1 reduces bioavailability of PGF and vascular endothelial growth factor (VEGF) l...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3269960/ https://ncbi.nlm.nih.gov/pubmed/21963217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.placenta.2011.08.008 |
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