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Antibiotic Evaluation and In Vivo Analysis of Alkynyl Coenzyme A Antimetabolites in Escherichia Coli

Pantothenamides have been the subject of much study as potential inhibitors of CoA and carrier protein dependent biosynthetic pathways. Based on an initial observation of growth inhibition in E. coli by 3, we have synthesized a small panel of pantetheine analogues and reexamined the inhibitory prope...

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Detalhes bibliográficos
Main Authors: Mercer, Andrew C., Meier, Jordan L., Hur, Gene H., Smith, Andrew R., Burkart, Michael D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269959/
https://ncbi.nlm.nih.gov/pubmed/18701278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.07.078
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