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Antibiotic Evaluation and In Vivo Analysis of Alkynyl Coenzyme A Antimetabolites in Escherichia Coli

Pantothenamides have been the subject of much study as potential inhibitors of CoA and carrier protein dependent biosynthetic pathways. Based on an initial observation of growth inhibition in E. coli by 3, we have synthesized a small panel of pantetheine analogues and reexamined the inhibitory prope...

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Bibliographic Details
Main Authors: Mercer, Andrew C., Meier, Jordan L., Hur, Gene H., Smith, Andrew R., Burkart, Michael D.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269959/
https://ncbi.nlm.nih.gov/pubmed/18701278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.07.078
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