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Anti-Neutrophil Cytoplasmic Antibodies Stimulate Release of Neutrophil Microparticles

The mechanisms by which anti-neutrophil cytoplasmic antibodies (ANCAs) may contribute to the pathogenesis of ANCA-associated vasculitis are not well understood. In this study, both polyclonal ANCAs isolated from patients and chimeric proteinase 3–ANCA induced the release of neutrophil microparticles...

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Detalhes bibliográficos
Main Authors: Hong, Ying, Eleftheriou, Despina, Hussain, Abdullah A.K., Price-Kuehne, Fiona E., Savage, Caroline O., Jayne, David, Little, Mark A., Salama, Alan D., Klein, Nigel J., Brogan, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269928/
https://ncbi.nlm.nih.gov/pubmed/22052057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011030298
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