Elevated Soluble Flt1 Inhibits Endothelial Repair in PR3-ANCA–Associated Vasculitis

Antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis exhibits endothelial damage, but the capacity for vessel repair in this disorder is not well understood. Here, we observed a marked increase in serum levels of soluble Flt1 (sFlt1), a potent inhibitor of vascular endothelial growth fac...

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Detalhes bibliográficos
Main Authors: Le Roux, Sandrine, Pepper, Ruth J., Dufay, Alexandre, Néel, Mélanie, Meffray, Emmanuelle, Lamandé, Noël, Rimbert, Marie, Josien, Régis, Hamidou, Mohamed, Hourmant, Maryvonne, Cook, H. Terence, Charreau, Béatrice, Larger, Etienne, Salama, Alan D., Fakhouri, Fadi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
Assuntos:
Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269927/
https://ncbi.nlm.nih.gov/pubmed/22034638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010080858
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