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Antifibrotic Effect of Tamoxifen in a Model of Progressive Renal Disease

Tamoxifen, a selective estrogen receptor modulator, has antifibrotic properties; however, whether it can attenuate renal fibrosis is unknown. In this study, we tested the effects of tamoxifen in a model of hypertensive nephrosclerosis (chronic inhibition of nitric oxide synthesis with L-NAME). After...

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Detalhes bibliográficos
Main Authors: Dellê, Humberto, Rocha, José Roberto C., Cavaglieri, Rita C., Vieira, José Mauro, Malheiros, Denise M.A.C., Noronha, Irene L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269918/
https://ncbi.nlm.nih.gov/pubmed/22052053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011010046
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