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Restoration of dystrophin expression using the Sleeping Beauty transposon
The Sleeping beauty (SB) system is a non-viral DNA based vector that has been used to stably integrate therapeutic genes into disease models. Here we report the SB system is capable of stably integrating the ΔR4-R23/CTΔ micro-dystrophin gene into a conditionally immortal dystrophin deficient muscle...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3269885/ https://ncbi.nlm.nih.gov/pubmed/22318674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/currents.RRN1296 |
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