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Potentiation of Anticancer Drugs: Effects of Pentoxifylline on Neoplastic Cells

The drug efflux activity of P-glycoprotein (P-gp, a product of the mdr1 gene, ABCB1 member of ABC transporter family) represents a mechanism by which tumor cells escape death induced by chemotherapeutics. In this study, we investigated the mechanisms involved in the effects of pentoxifylline (PTX) o...

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Autors principals: Barancik, Miroslav, Bohacova, Viera, Gibalova, Lenka, Sedlak, Jan, Sulova, Zdena, Breier, Albert
Format: Artigo
Idioma:Inglês
Publicat: Molecular Diversity Preservation International (MDPI) 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269692/
https://ncbi.nlm.nih.gov/pubmed/22312258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13010369
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