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Membrane microdomain sphingolipids are required for anti-CD20-induced death of chronic lymphocytic leukemia B cells

BACKGROUND: Chronic lymphocytic leukemia remains incurable, despite the addition of rituximab to chemotherapy as an available means of treatment. The resistance of certain patients to this monoclonal antibody prompted us to set up in vitro studies of another CD20-specific monoclonal antibody, B1 (la...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hammadi, Mariam, Youinou, Pierre, Tempescul, Adrian, Tobón, Gabriel, Berthou, Christian, Bordron, Anne, Pers, Jacques-Olivier
Format: Artigo
Sprache:Inglês
Veröffentlicht: Ferrata Storti Foundation 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269491/
https://ncbi.nlm.nih.gov/pubmed/22058197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.051938
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