Increased GABA(A) Receptor ε-Subunit Expression on Ventral Respiratory Column Neurons Protects Breathing during Pregnancy

GABAergic signaling is essential for proper respiratory function. Potentiation of this signaling with allosteric modulators such as anesthetics, barbiturates, and neurosteroids can lead to respiratory arrest. Paradoxically, pregnant animals continue to breathe normally despite nearly 100-fold increa...

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Библиографические подробности
Главные авторы: Hengen, Keith B., Nelson, Nathan R., Stang, Kyle M., Johnson, Stephen M., Crader, Stephanie M., Watters, Jyoti J., Mitchell, Gordon S., Behan, Mary
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269439/
https://ncbi.nlm.nih.gov/pubmed/22303446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030608
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