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Targeting STAT4 in systemic sclerosis: a promising new direction

STAT4 has been identified as a genetic risk factor for the development of autoimmune diseases including systemic sclerosis. STAT4 regulates Th1 cell development and cell-mediated immunity, but it is not known how it may regulate the development of dermal fibrosis. Using the bleomycin-induced dermal...

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Main Authors: Barnes, Jammie, Agarwal, Sandeep K
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269303/
https://ncbi.nlm.nih.gov/pubmed/21790287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/eci.11.31
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