Synthesis and physical characterization of the self-complementary, alternating pyrimidine/purine hexanucleotide d[CGTACG].

The hexanucleotide d(CGTACG) has been synthesized by a phosphotriester method in which, for the first time, an O-6 protected deoxyguanosine derivative has been used to avoid side reactions of the guanine residues. Conformational analysis by circular dichroism shows that d(CGTACG) maintains a B form...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Kuzmich, S, Marky, L A, Jones, R A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1982
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326916/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7177847/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/10.20.6265
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