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Effects of age and caloric restriction on mitochondrial protein oxidative damage in mice

The hypothesis that life span extension by caloric restriction (CR) is contingent upon the attenuation of macromolecular oxidative damage was tested in two different strains of mice: the C57BL/6, whose life span is extended by CR, and the DBA/2, in which CR has relatively minor or no impact on longe...

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Autors principals: Li, Xiao-Dong, Rebrin, Igor, Forster, Michael J., Sohal, Rajindar S.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268905/
https://ncbi.nlm.nih.gov/pubmed/22182424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2011.12.001
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