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Evaluation of copper-64-labeled somatostatin agonists and antagonist in sstr2-transfected cell lines that are positive and negative for p53: implications for cancer therapy

OBJECTIVES: Radiolabeled somatostatin analogs have become important agents for molecular imaging and targeted radiotherapy of somatostatin receptor-positive tumors. Here we determine the effect of the tumor suppressor protein, p53, on trafficking (64)Cu to tumor cell nuclei from DOTA vs.CB-TE2A-conj...

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Detalhes bibliográficos
Principais autores: Nguyen, Kim, Parry, Jesse J., Rogers, Buck E., Anderson, Carolyn J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268844/
https://ncbi.nlm.nih.gov/pubmed/22056254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2011.08.006
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