CCL2 Is Associated with a Faster Rate of Cognitive Decline during Early Stages of Alzheimer's Disease

Chemokine (C-C motif) receptor 2 (CCR2)-signaling can mediate accumulation of microglia at sites affected by neuroinflammation. CCR2 and its main ligand CCL2 (MCP-1) might also be involved in the altered metabolism of beta-amyloid (Aβ) underlying Alzheimer's disease (AD). We therefore measured...

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Bibliografiske detaljer
Main Authors: Westin, Karin, Buchhave, Peder, Nielsen, Henrietta, Minthon, Lennart, Janciauskiene, Sabina, Hansson, Oskar
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268759/
https://ncbi.nlm.nih.gov/pubmed/22303443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030525
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