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Ribosomal Route to Small Molecule Diversity
The cyanobactin ribosomal peptide (RP) natural product pathway was manipulated to incorporate multiple tandem mutations and non-proteinogenic amino acids, using eight heterologous components simultaneously expressed in Escherichia coli. These studies reveal the potential of RPs for the rational synt...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268757/ https://ncbi.nlm.nih.gov/pubmed/22107593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja208278k |
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