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Experimental procedure for the characterization of radiation damage in macromolecular crystals

A reliable and reproducible method to automatically characterize the radiation sensitivity of macromolecular crystals at the ESRF beamlines has been developed. This new approach uses the slope of the linear dependence of the overall isotropic B-factor with absorbed dose as the damage metric. The met...

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Detalhes bibliográficos
Main Authors: Leal, Ricardo M. F., Bourenkov, Gleb P., Svensson, Olof, Spruce, Darren, Guijarro, Matias, Popov, Alexander N.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268693/
https://ncbi.nlm.nih.gov/pubmed/21525646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0909049511002251
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