Genetic and Physical Interaction of the B-Cell SLE-Associated Genes BANK1 and BLK

OBJECTIVES: Altered signaling in B-cells is a predominant feature of systemic lupus erythematosus (SLE). The genes BANK1 and BLK were recently described as associated with SLE. BANK1 codes for a B-cell-specific cytoplasmic protein involved in B-cell receptor signaling and BLK codes for an Src tyrosi...

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Autori principali: Castillejo-López, Casimiro, Delgado-Vega, Angélica M., Wojcik, Jerome, Kozyrev, Sergey V., Thavathiru, Elangovan, Wu, Ying-Yu, Sánchez, Elena, Pöllmann, David, López-Egido, Juan R., Fineschi, Serena, Domínguez, Nicolás, Lu, Rufei, James, Judith A., Merrill, Joan T., Kelly, Jennifer A., Kaufman, Kenneth M., Moser, Kathy, Gilkeson, Gary, Frostegård, Johan, Pons-Estel, Bernardo A., D’Alfonso, Sandra, Witte, Torsten, Callejas, José Luis, Harley, John B., Gaffney, Patrick, Martin, Javier, Guthridge, Joel M., Alarcón-Riquelme, Marta E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268679/
https://ncbi.nlm.nih.gov/pubmed/21978998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2011-200085
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