TCF12 Protein Functions as Transcriptional Repressor of E-cadherin, and Its Overexpression Is Correlated with Metastasis of Colorectal Cancer

A correlation of TCF12 mRNA overexpression with colorectal cancer (CRC) metastasis was suggested by microarray data and validated by the survey of 120 patients. Thirty-three (27.5%) of the 120 patients showed tumor TCF12 mRNA overexpression and had a higher rate of metastatic occurrence (p = 0.020)...

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Detalhes bibliográficos
Main Authors: Lee, Chun-Chung, Chen, Wei-Shone, Chen, Chia-Chi, Chen, Li-Li, Lin, Yi-Shing, Fan, Chi-Shuan, Huang, Tze-Sing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268437/
https://ncbi.nlm.nih.gov/pubmed/22130667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.258947
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