Comparative Lipidomic Analysis of Mouse and Human Brain with Alzheimer Disease

Lipids are key regulators of brain function and have been increasingly implicated in neurodegenerative disorders including Alzheimer disease (AD). Here, a systems-based approach was employed to determine the lipidome of brain tissues affected by AD. Specifically, we used liquid chromatography-mass s...

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Autors principals: Chan, Robin B., Oliveira, Tiago G., Cortes, Etty P., Honig, Lawrence S., Duff, Karen E., Small, Scott A., Wenk, Markus R., Shui, Guanghou, Di Paolo, Gilbert
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Lipids
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268426/
https://ncbi.nlm.nih.gov/pubmed/22134919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.274142
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