Fibroblast Growth Factor 9 (FGF9)-Pituitary Homeobox 2 (PITX2) Pathway Mediates Transforming Growth Factor β (TGFβ) Signaling to Regulate Cell Proliferation in Palatal Mesenchyme during Mouse Palatogenesis

Cleft palate represents one of the most common congenital birth defects. Transforming growth factor β (TGFβ) signaling plays crucial functions in regulating craniofacial development, and loss of TGFβ receptor type II in cranial neural crest cells leads to craniofacial malformations, including cleft...

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Bibliographische Detailangaben
Hauptverfasser: Iwata, Jun-ichi, Tung, Lily, Urata, Mark, Hacia, Joseph G., Pelikan, Richard, Suzuki, Akiko, Ramenzoni, Liza, Chaudhry, Obaid, Parada, Carolina, Sanchez-Lara, Pedro A., Chai, Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268397/
https://ncbi.nlm.nih.gov/pubmed/22123828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.280974
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