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Interplay between statins and PPARs in improving cardiovascular outcomes: a double-edged sword?

Statins are best-selling medications in the management of high cholesterol and associated cardiovascular complications. They inhibit 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)-reductase in order to prevent disproportionate cholesterol synthesis. Statins slow the progression of atherosclerosis,...

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Bibliografske podrobnosti
Main Authors: Balakumar, Pitchai, Mahadevan, Nanjaian
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268191/
https://ncbi.nlm.nih.gov/pubmed/21790534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01597.x
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