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Quality Control Issues and the Identification of Rare Functional Variants with Next-Generation Sequencing Data
Next-generation sequencing of large numbers of individuals presents challenges in data preparation, quality control, and statistical analysis because of the rarity of the variants. The Genetic Analysis Workshop 17 (GAW17) data provide an opportunity to survey existing methods and compare these metho...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268158/ https://ncbi.nlm.nih.gov/pubmed/22128054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20645 |
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