A negative screen for mutations in calstabin 1 and 2 genes in patients with dilated cardiomyopathy

BACKGROUND: Calstabins 1 and 2 bind to Ryanodine receptors regulating muscle excitation-contraction coupling. Mutations in Ryanodine receptors affecting their interaction with calstabins lead to different cardiac pathologies. Animal studies suggest the involvement of calstabins with dilated cardiomy...

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Main Authors: Biagi, Diogo G, Mill, José G, Mansur, Alfredo J, Krieger, José E, Pereira, Alexandre C
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2012
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268099/
https://ncbi.nlm.nih.gov/pubmed/22236651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5751-11-4
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