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A negative screen for mutations in calstabin 1 and 2 genes in patients with dilated cardiomyopathy
BACKGROUND: Calstabins 1 and 2 bind to Ryanodine receptors regulating muscle excitation-contraction coupling. Mutations in Ryanodine receptors affecting their interaction with calstabins lead to different cardiac pathologies. Animal studies suggest the involvement of calstabins with dilated cardiomy...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3268099/ https://ncbi.nlm.nih.gov/pubmed/22236651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5751-11-4 |
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