A negative screen for mutations in calstabin 1 and 2 genes in patients with dilated cardiomyopathy

BACKGROUND: Calstabins 1 and 2 bind to Ryanodine receptors regulating muscle excitation-contraction coupling. Mutations in Ryanodine receptors affecting their interaction with calstabins lead to different cardiac pathologies. Animal studies suggest the involvement of calstabins with dilated cardiomy...

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Bibliografiske detaljer
Main Authors: Biagi, Diogo G, Mill, José G, Mansur, Alfredo J, Krieger, José E, Pereira, Alexandre C
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268099/
https://ncbi.nlm.nih.gov/pubmed/22236651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5751-11-4
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