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A Comparison of Two Yeast MnSODs: Mitochondrial Saccharomyces cerevisiae versus Cytosolic Candida albicans

Human MnSOD is significantly more product-inhibited than bacterial MnSODs at high concentrations of superoxide (O(2)(−)). This behavior limits the amount of H(2)O(2) produced at high [O(2)(−)]; its desirability can be explained by the multiple roles of H(2)O(2) in mammalian cells, particularly its r...

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Détails bibliographiques
Auteurs principaux: Sheng, Yuewei, Stich, Troy A., Barnese, Kevin, Gralla, Edith B., Cascio, Duilio, Britt, R. David, Cabelli, Diane E., Valentine, Joan Selverstone
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268005/
https://ncbi.nlm.nih.gov/pubmed/22077216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2077476
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