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Estimation and Visualization of Identity-by-Descent within Pedigrees Simplifies Interpretation of Complex Trait Analysis

Linkage analysis identifies markers that appear to be co-inherited with a trait within pedigrees. The inheritance of a chromosomal segment may be probabilistically reconstructed, with missing data complicating inference. Inheritance patterns are further obscured in the analysis of complex traits, wh...

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Detalhes bibliográficos
Main Authors: Marchani, Elizabeth E., Wijsman, Ellen M.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267995/
https://ncbi.nlm.nih.gov/pubmed/22189471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000334083
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