NAD(P)H:QUINONE OXIOREDUCTASE 1 PROTECTS LUNGS FROM OXIDANT-INDUCED EMPHYSEMA IN MICE

Emphysema is currently a leading cause of mortality with no known effective therapy to attenuate progressive loss of lung function. Previous work support that activation of nuclear factor erythroid 2-related factor 2 (Nrf2) is protective to the lung through induction of hundreds of antioxidant genes...

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Autores principales: Potts-Kant, Erin N., Li, Zhuowei, Tighe, Robert M., Lindsey, James Y., Frush, Benjamin W., Foster, W. Michael, Hollingsworth, John W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267893/
https://ncbi.nlm.nih.gov/pubmed/22198263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.11.027
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