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Nucleocapsid Protein Annealing of a Primer-Template Enhances (+)-Strand DNA Synthesis and Fidelity by HIV-1 Reverse Transcriptase

Human immunodeficiency virus type-1 (HIV-1) requires reverse transcriptase (RT) and HIV-1 nucleocapsid protein (NCp7) for proper viral replication. HIV-1 NCp7 has been shown to enhance various steps in reverse transcription including tRNA initiation and strand transfer which may be mediated through...

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Detalhes bibliográficos
Main Authors: Kim, Jiae, Roberts, Anne, Yuan, Hua, Xiong, Yong, Anderson, Karen S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267859/
https://ncbi.nlm.nih.gov/pubmed/22210155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.12.034
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