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Ribosomal RNA cleavage, nuclease activation and 2-5A(ppp(A2'p)nA) in interferon-treated cells.

Ribosomal RNA (rRNA) in intact ribosomes is cleaved into discrete products on incubation of reticulocyte lysates or L-cell extracts with ppp(A2'p)3A. Cleavage of rRNA may, therefore, provide a useful assay for 2-5A (ppp)A2'p)nA; n = 2 to 4) or for the presence of a 2-5A-dependent nuclease. The resul...

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Udgivet i:Nucleic Acids Res
Principais autores: Wreschner, D H, James, T C, Silverman, R H, Kerr, I M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1981
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC326782/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6164990/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/9.7.1571
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