Lack of prognostic significance of p16 and p27 after radical prostatectomy in hormone-naïve prostate cancer

BACKGROUND: Loss of normal cell cycle control is an early event in the evolution of cancer. The expression of cyclin-dependent kinase (CDK) inhibitors p16 and p27 has been previously associated with progression of prostate cancer (PC). 70 patients diagnosed with early stage PCwere treated with radic...

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Autores principales: Vlachostergios, Panagiotis J, Karasavvidou, Foteini, Kakkas, Grigorios, Kapatou, Kassiani, Gioulbasanis, Ioannis, Daliani, Danai D, Moutzouris, George, Papandreou, Christos N
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267667/
https://ncbi.nlm.nih.gov/pubmed/22221586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-5751-11-2
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