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Filamin-A as a marker and target for DNA damage based cancer therapy

Filamin-A, also called actin binding protein 280 (ABP-280), cross-links the actin filaments into dynamic orthogonal network to serve as scaffolds in multiple signaling pathways. It has been reported that filamin-A interacts with DNA damage response proteins BRCA1 and BRCA2. Defects of filamin-A impa...

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Detalhes bibliográficos
Main Authors: Yue, Jingyin, Lu, Huimei, Liu, Jingmei, Berwick, Marianne, Shen, Zhiyuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267325/
https://ncbi.nlm.nih.gov/pubmed/22051193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.10.019
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