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Prolyl Oligopeptidase, Inositol Phosphate Signalling and Lithium Sensitivity

Inhibition of prolyl oligopeptidase (PO) elevates inositol phosphate (IP) signalling and reduces cell sensitivity to lithium (Li(+)). This review discusses recent evidence that shows PO acts via the multiple inositol polyphosphate phosphatase (MIPP) to regulate gene expression. As a consequence, PO...

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Autor principal: Harwood, Adrian J
Format: Artigo
Idioma:Inglês
Publicat: Bentham Science Publishers 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3267164/
https://ncbi.nlm.nih.gov/pubmed/21222625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/187152711794653779
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