Functional analysis of missense variants in the TRESK (KCNK18) K(+) channel

A loss of function mutation in the TRESK K2P potassium channel (KCNK18), has recently been linked with typical familial migraine with aura. We now report the functional characterisation of additional TRESK channel missense variants identified in unrelated patients. Several variants either had no app...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Andres-Enguix, Isabelle, Shang, Lijun, Stansfeld, Phillip J., Morahan, Julia M., Sansom, Mark S. P., Lafrenière, Ronald G., Roy, Bishakha, Griffiths, Lyn R., Rouleau, Guy A., Ebers, George C., Cader, Zameel M., Tucker, Stephen J.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266952/
https://ncbi.nlm.nih.gov/pubmed/22355750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00237
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