Systems Biology Approaches Reveal a Specific Interferon-Inducible Signature in HTLV-1 Associated Myelopathy

Human T-lymphotropic virus type 1 (HTLV-1) is a retrovirus that persists lifelong in the host. In ∼4% of infected people, HTLV-1 causes a chronic disabling neuroinflammatory disease known as HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The pathogenesis of HAM/TSP is unknown a...

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Detalhes bibliográficos
Main Authors: Tattermusch, Sonja, Skinner, Jason A., Chaussabel, Damien, Banchereau, Jacques, Berry, Matthew P., McNab, Finlay W., O'Garra, Anne, Taylor, Graham P., Bangham, Charles R. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266939/
https://ncbi.nlm.nih.gov/pubmed/22291590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002480
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