The Viral and Cellular MicroRNA Targetome in Lymphoblastoid Cell Lines

Epstein-Barr virus (EBV) is a ubiquitous human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially...

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Autores principales: Skalsky, Rebecca L., Corcoran, David L., Gottwein, Eva, Frank, Christopher L., Kang, Dong, Hafner, Markus, Nusbaum, Jeffrey D., Feederle, Regina, Delecluse, Henri-Jacques, Luftig, Micah A., Tuschl, Thomas, Ohler, Uwe, Cullen, Bryan R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266933/
https://ncbi.nlm.nih.gov/pubmed/22291592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002484
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